HUBUNGAN HIPO-HDL DENGAN KEJADIAN PENYAKIT JANTUNG KORONER DI RSUD DR. ZAINOEL ABIDIN KOTA BANDA ACEH
DOI:
https://doi.org/10.51878/healthy.v5i4.15399Keywords:
Aterosklerosisi, Dislipidemia, Hipo-HDL, Penyakit Jantung Koroner, Sindrom Koroner AkutAbstract
Coronary artery disease (CAD) is a major cause of morbidity and mortality associated with atherosclerosis. Low levels of high-density lipoprotein (HDL), or hypo-HDL, may be associated with an increased risk of coronary events. This study aimed to analyze the association between hypo-HDL and CAD based on the diagnoses of unstable angina pectoris (UAP), non-ST-elevation myocardial infarction (NSTEMI), and ST-elevation myocardial infarction (STEMI) at Dr. Zainoel Abidin Regional General Hospital, Banda Aceh. A quantitative study with a cross-sectional design was conducted using secondary data from medical records for January–December 2025. The sample consisted of 93 patients, including 31 UAP, 31 NSTEMI, and 31 STEMI patients, selected using simple random sampling. Data were analyzed using univariate and bivariate analyses with the Chi-Square test at α=0.05. A total of 66 respondents (71%) had low HDL levels. The analysis showed significant associations between HDL levels and UAP (p=0.000), NSTEMI (p=0.022), and STEMI (p=0.022). Thus, hypo-HDL was associated with variations in CAD diagnoses in this study. HDL monitoring may be considered as part of CAD risk-factor management.
ABSTRAK
Penyakit jantung koroner (PJK) merupakan salah satu penyebab utama morbiditas dan mortalitas akibat aterosklerosis. Kadar high-density lipoprotein (HDL) yang rendah atau hipo-HDL dapat berkaitan dengan peningkatan risiko kejadian koroner. Penelitian ini bertujuan menganalisis hubungan hipo-HDL dengan kejadian PJK berdasarkan diagnosis unstable angina pectoris (UAP), non-ST-elevation myocardial infarction (NSTEMI), dan ST-elevation myocardial infarction (STEMI) di RSUD Dr. Zainoel Abidin Banda Aceh. Penelitian menggunakan metode kuantitatif dengan desain cross-sectional dan data sekunder rekam medis periode Januari–Desember 2025. Sampel berjumlah 93 pasien, terdiri atas 31 pasien UAP, 31 NSTEMI, dan 31 STEMI, yang dipilih menggunakan simple random sampling. Data dianalisis secara univariat dan bivariat menggunakan uji Chi-Square dengan α=0,05. Sebanyak 66 responden (71%) memiliki kadar HDL rendah. Hasil analisis menunjukkan hubungan signifikan antara kadar HDL dan diagnosis UAP (p=0,000), NSTEMI (p=0,022), serta STEMI (p=0,022). Dengan demikian, hipo-HDL berhubungan dengan variasi diagnosis PJK pada penelitian ini. Pemantauan kadar HDL dapat dipertimbangkan sebagai bagian dari pengendalian faktor risiko PJK.
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