GAMBARAN KARAKTERISTIK PASIEN HEMODIALISIS YANG MENDAPATKAN TRANSFUSI DARAH SELAMA ENAM BULAN: STUDI DESKRIPTIF RETROSPEKTIF

Authors

  • Siti Safaah Ruang Hemodialisis, RSUD Ajibarang, Banyumas

Keywords:

Anemia, Hemodialisis, Penyakit Ginjal Kronik, Transfusi Darah, Hemoglobin, Studi Deskriptif

Abstract

Anemia is commonly found in patients with chronic kidney disease (CKD) undergoing hemodialysis and may require red blood cell transfusions. This study aimed to describe transfusion episodes at Ajibarang Regional General Hospital from January to June 2026. A retrospective descriptive observational design was employed, covering 256 transfusion episodes involving 89 unique patients. Clinical data, pre-transfusion hemoglobin (Hb) levels, vascular access, CKD diagnoses, and transfusion frequency were analyzed descriptively. Episode characteristics were calculated using 256 episodes as the denominator, while recurrent transfusions were calculated based on 89 patients. The mean pre-transfusion Hb level was 7.06 ± 0.78 g/dL, with all episodes having Hb levels below 8 g/dL. A total of 170 episodes (66.4%) had Hb levels ranging from 7.0 to 7.9 g/dL. Cimino/arteriovenous fistula (AVF) access was recorded in 52.3% of episodes, while femoral access accounted for 44.9%. Hypertension was the most frequently recorded CKD etiology (68.8%). Sixty-nine patients (77.5%) experienced at least two transfusion episodes. These findings support the need for anemia and transfusion audits integrating Hb levels, clinical indications, iron status, anemia treatment, and vascular access documentation. This study provides a baseline description of local services but does not assess transfusion prevalence in the entire hemodialysis population or the clinical appropriateness of individual transfusion decisions.

ABSTRAK

Anemia sering ditemukan pada pasien penyakit ginjal kronik (PGK) yang menjalani hemodialisis dan memerlukan transfusi sel darah merah. Penelitian ini bertujuan menggambarkan episode transfusi di RSUD Ajibarang selama Januari–Juni 2026. Penelitian menggunakan desain observasional deskriptif retrospektif, meliputi 256 episode transfusi dari 89 pasien unik. Data klinis, Hb pra-transfusi, akses vaskular, diagnosis PGK, dan frekuensi transfusi dianalisis. Karakteristik episode dihitung berdasarkan 256 episode, sedangkan transfusi berulang berdasarkan 89 pasien. Rerata Hb pra-transfusi sebesar 7,06 ± 0,78 g/dL dan seluruh episode memiliki Hb di bawah 8 g/dL. Sebanyak 170 episode (66,4%) berada pada rentang 7,0–7,9 g/dL. Akses Cimino/arteriovenous fistula (AVF) tercatat pada 52,3% episode dan akses femoral pada 44,9%. Hipertensi merupakan diagnosis PGK yang dicatat (68,8%). Sebanyak 69 pasien (77,5%) mengalami sedikitnya dua episode transfusi. Temuan ini mendukung audit anemia dan transfusi yang mengintegrasikan Hb, indikasi klinis, status besi, terapi anemia, serta dokumentasi akses vaskular. Penelitian memberikan gambaran pelayanan lokal, tetapi tidak menilai prevalensi transfusi populasi hemodialisis atau ketepatan keputusan transfusi.

Downloads

Download data is not yet available.

References

Anumas, S., Chatkrailert, A., & Tantiyavarong, P. (2023). Maintenance intravenous iron in hemodialysis patients to minimize erythropoietin doses: A double-blinded, randomized controlled trial (the MAINTAIN IRON trial). Scientific Reports, 13, 1287. https://doi.org/10.1038/s41598-023-28440-3

Badura, K., Janc, J., W?sik, J., Gnitecki, S., Skwira, S., M?ynarska, E., Rysz, J., & Franczyk, B. (2024). Anemia of chronic kidney disease—A narrative review of its pathophysiology, diagnosis, and management. Biomedicines, 12(6), 1191. https://doi.org/10.3390/biomedicines12061191

Carson, J. L., Stanworth, S. J., Guyatt, G., Valentine, S., Dennis, J., Bakhtary, S., Cohn, C. S., Dubon, A., Grossman, B. J., Gupta, G. K., Hess, A. S., Lesser, M. L., & Rao, S. V. (2023). Red blood cell transfusion: 2023 AABB international guidelines. JAMA, 330(19), 1892–1902. https://doi.org/10.1001/jama.2023.12914

Chan, R. J., & Chan, C. T. (2024). Vascular access considerations in home hemodialysis. Clinical Journal of the American Society of Nephrology, 19(8), 1036–1044. https://doi.org/10.2215/CJN.0000000000000499

Chung, E. Y. M., Palmer, S. C., Saglimbene, V. M., Craig, J. C., Tonelli, M., & Strippoli, G. F. M. (2023). Erythropoiesis-stimulating agents for anaemia in adults with chronic kidney disease: A network meta-analysis. Cochrane Database of Systematic Reviews, 2023(2), CD010590. https://doi.org/10.1002/14651858.CD010590.pub3

Dasgupta, I., Isnard Bagnis, C., Floris, M., Furuland, H., Gallego Zurro, D., Gesualdo, L., Heirman, N., Minutolo, R., Pani, A., Portolés, J., Rosenberger, C., Sánchez Alvarez, J. E., Ureña Torres, P., Vanholder, R. C., & Wanner, C. (2024). Anaemia and quality of life in chronic kidney disease: A consensus document from the European Anaemia of CKD Alliance. Clinical Kidney Journal, 17(8), sfae205. https://doi.org/10.1093/ckj/sfae205

Fuertinger, D. H., Wang, L.-C., Jörg, D. J., Rivera Fuentes, L., Ye, X., Casper, S., Zhang, H., Mermelstein, A., Cherif, A., Ho, K., Raimann, J. G., Tisdale, L., Kotanko, P., & Thijssen, S. (2024). Effects of individualized anemia therapy on hemoglobin stability: A randomized controlled pilot trial in patients on hemodialysis. Clinical Journal of the American Society of Nephrology, 19(9), 1138–1147. https://doi.org/10.2215/CJN.0000000000000488

Hain, D., Bednarski, D., Cahill, M., Dix, A., Foote, B., Haras, M. S., Pace, R., & Gutiérrez, O. M. (2023). Iron-deficiency anemia in CKD: A narrative review for the kidney care team. Kidney Medicine, 5(8), 100677. https://doi.org/10.1016/j.xkme.2023.100677

Jonny, J., Sitepu, E. C., Azzalyka, K. A., & Pasiak, T. F. (2023). Hepcidin in hemodialysis patients: An update review. Turkish Journal of Nephrology, 32(4), 277–283. https://doi.org/10.5152/turkjnephrol.2023.22422

Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. (2024). KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney International, 105(4 Suppl.), S117–S314. https://doi.org/10.1016/j.kint.2023.10.018

Kidney Disease: Improving Global Outcomes (KDIGO) Anemia Work Group. (2026). KDIGO 2026 clinical practice guideline for the management of anemia in chronic kidney disease (CKD). Kidney International, 109(Suppl. 1S), S1–S99. https://doi.org/10.1016/j.kint.2025.06.006

Kuragano, T. (2024). Treatment of anemia associated with chronic kidney disease: Plea for considering physiological erythropoiesis. International Journal of Molecular Sciences, 25(13), 7322. https://doi.org/10.3390/ijms25137322

Li, J., Lu, H., Xie, Z., Li, Q., & Shi, H. (2023). Outcomes of arteriovenous graft vs. fistula for haemodialysis access in the elderly: A systematic review and meta-analysis. Experimental and Therapeutic Medicine, 26(2), 399. https://doi.org/10.3892/etm.2023.12098

Liu, Y., Yang, R., Teng, W., Gu, L., Yu, C., Du, Z., Li, Y., Zang, X., Chao, J., & Yu, H. (2025). Anemia, iron metabolism, and anemia medication habits in patients undergoing maintenance hemodialysis and peritoneal dialysis are different: A multicenter investigation. Clinical and Experimental Nephrology, 29(5), 573–582. https://doi.org/10.1007/s10157-024-02594-4

Lok, C. E., Huber, T. S., Orchanian-Cheff, A., & Rajan, D. K. (2024). Arteriovenous access for hemodialysis: A review. JAMA, 331(15), 1307–1317. https://doi.org/10.1001/jama.2024.0535

Macdougall, I. C. (2024). Anaemia in CKD—Treatment standard. Nephrology Dialysis Transplantation, 39(5), 770–777. https://doi.org/10.1093/ndt/gfad250

Peralta, R., Sousa, L., & Cristovão, A. F. (2023). Cannulation technique of vascular access in hemodialysis and the impact on the arteriovenous fistula survival: Systematic review and meta-analysis. Journal of Clinical Medicine, 12(18), 5946. https://doi.org/10.3390/jcm12185946

Stoumpos, S., Crowe, K., Sarafidis, P., Barratt, J., Bolignano, D., Del Vecchio, L., Ma?yszko, J., Wi?cek, A., Ortiz, A., & Cozzolino, M. (2024). Hypoxia-inducible factor prolyl hydroxylase inhibitors for anaemia in chronic kidney disease: A clinical practice document by the European Renal Best Practice board of the European Renal Association. Nephrology Dialysis Transplantation, 39(10), 1710–1730. https://doi.org/10.1093/ndt/gfae075

Wetmore, J. B., Rouette, J., Richards, A., Guo, H., Requena, G., Li, S., Mu, G., Ma, L., Gilbertson, D. T., Wetten, S., & Liu, J. (2026). Anemia treatment and its clinical implications in patients receiving hemodialysis hyporesponsive to erythropoietin-stimulating agents. Kidney Medicine, 8(4), 101269. https://doi.org/10.1016/j.xkme.2026.101269

Willicombe, M., & Roberts, D. J. (2024). Transfusion-induced HLA sensitization in wait-list patients and kidney transplant recipients. Kidney International, 106(5), 795–805. https://doi.org/10.1016/j.kint.2024.07.030

Young, E. W., Wang, D., Kapke, A., Pearson, J., Turenne, M., Robinson, B. M., & Huff, E. D. (2023). Hemoglobin and clinical outcomes in hemodialysis: An analysis of US Medicare data from 2018 to 2020. Kidney Medicine, 5(2), 100578. https://doi.org/10.1016/j.xkme.2022.100578

Downloads

Published

2026-11-13

How to Cite

Safaah, S. (2026). GAMBARAN KARAKTERISTIK PASIEN HEMODIALISIS YANG MENDAPATKAN TRANSFUSI DARAH SELAMA ENAM BULAN: STUDI DESKRIPTIF RETROSPEKTIF. MEDIKA : Jurnal Kasus Dan Penelitian Kesehatan, 2(1), 396–406. Retrieved from https://www.jurnalp4i.com/index.php/medika/article/view/16815

Issue

Section

Articles

Similar Articles

1 2 3 > >> 

You may also start an advanced similarity search for this article.