THE UNPLEASANT TRUTH: EXPLORING THE COMPLEXITIES OF HALITOSIS
DOI:
https://doi.org/10.51878/science.v5i2.4879Keywords:
halitosis, bad breath, oral hygieneAbstract
Halitosis, or bad breath, is a common condition that can significantly affect an individual’s quality of life and social interactions. It results from a complex interaction of multiple etiological factors, predominantly originating within the oral cavity such as the activity of anaerobic microbes producing volatile sulfur compounds (VSCs), but also greatly influenced by systemic health status, diet, and lifestyle choices. Effective management therefore requires a comprehensive and careful diagnostic approach, not only to identify specific etiological factors such as the level of oral hygiene, periodontal health, and the presence or absence of xerostomia, but also to uncover potential contributions from underlying systemic medical conditions and dietary intake. This paper aims to present a comprehensive review of current concepts in the diagnosis and management of halitosis. Successful halitosis management strategies rely heavily on the pillars of ongoing patient education, the development of a personalized treatment plan based on the underlying cause—including mechanical and chemical interventions—and regular clinical monitoring and follow-up. Furthermore, interdisciplinary collaboration, combining expertise from dentistry, oral microbiology, internal medicine, and psychology, is crucial to advance more accurate diagnostic approaches and more effective therapeutic options. Thus, the importance of implementing a holistic, interdisciplinary, patient-centered approach to improve overall oral health and enhance overall patient well-being is emphasized.
ABSTRAK
Halitosis, atau bau mulut, adalah kondisi umum yang dapat memengaruhi kualitas hidup dan interaksi sosial seseorang secara signifikan. Hal ini disebabkan oleh interaksi kompleks berbagai faktor etiologi, yang sebagian besar berasal dari rongga mulut seperti aktivitas mikroba anaerobik yang menghasilkan senyawa sulfur volatil (VSC), tetapi juga sangat dipengaruhi oleh status kesehatan sistemik, pola makan, dan pilihan gaya hidup. Oleh karena itu, penanganan yang efektif memerlukan pendekatan diagnostik yang komprehensif dan cermat, tidak hanya untuk mengidentifikasi faktor etiologi tertentu seperti tingkat kebersihan mulut, kesehatan periodontal, dan ada atau tidaknya xerostomia, tetapi juga untuk mengungkap potensi kontribusi dari kondisi medis sistemik yang mendasarinya dan asupan makanan. artikel ini bertujuan untuk menyajikan tinjauan komprehensif tentang konsep terkini dalam diagnosis dan penanganan halitosis. Strategi penanganan halitosis yang berhasil sangat bergantung pada pilar-pilar edukasi pasien yang berkelanjutan, pengembangan rencana perawatan yang dipersonalisasi berdasarkan penyebab yang mendasarinya termasuk intervensi mekanis dan kimia dan pemantauan dan tindak lanjut klinis yang teratur. Lebih jauh lagi, kolaborasi interdisipliner, yang menggabungkan keahlian dari kedokteran gigi, mikrobiologi oral, penyakit dalam, dan psikologi, sangat penting untuk memajukan pendekatan diagnostik yang lebih akurat dan pilihan terapi yang lebih efektif. Dengan demikian, pentingnya menerapkan pendekatan holistik, interdisipliner, dan berpusat pada pasien untuk meningkatkan kesehatan mulut secara keseluruhan dan meningkatkan kesejahteraan pasien secara keseluruhan ditekankan.
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References
Aitha, H. et al. (2015). Xerostomia: An overview. Journal of Indian Academy of Oral Medicine and Radiology, 27(1), 85. https://doi.org/10.4103/0972-1363.167104
Alhejoury, H. A. et al. (2021). Artificial saliva for therapeutic management of xerostomia. Journal of Pharmacy And Bioallied Sciences, 13, S236. https://doi.org/10.4103/jpbs.jpbs_236_21 (Catatan: "S236" menunjukkan nomor artikel atau halaman suplemen, halaman spesifik untuk "13" tidak jelas dari input)
Alkalash, S. H. et al. (2023). A cross-sectional study on the knowledge, attitudes, and oral hygiene practices of secondary school students in Al-Qunfudah district, Saudi Arabia. Cureus. https://doi.org/10.7759/cureus.40337
Almståhl, A., & Wikström, M. (1999). Oral microflora in subjects with reduced salivary secretion. Journal of Dental Research, 78(8), 1410. https://doi.org/10.1177/00220345990780080601
Anil, S. et al. (2014). Xerostomia in geriatric patients: A burgeoning global concern. Journal of Investigative and Clinical Dentistry, 7(1), 5. https://doi.org/10.1111/jicd.12120
Arigbede, A. et al. (2012). Periodontitis and systemic diseases: A literature review. Journal of Indian Society of Periodontology, 16(4), 487. https://doi.org/10.4103/0972-124x.106878
Atkinson, J. C. et al. (2005). Salivary hypofunction and xerostomia: Diagnosis and treatment. Dental Clinics of North America, 49(2), 309. https://doi.org/10.1016/j.cden.2004.10.002
Barranca-Enríquez, A., & Romo?González, T. (2022). Your health is in your mouth: A comprehensive view to promote general wellness. Frontiers in Oral Health, 3. https://doi.org/10.3389/froh.2022.971223
Figdor, D. (2002). Apical periodontitis: A very prevalent problem. Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 94(6), 651. https://doi.org/10.1067/moe.2002.130322
Gaines, A. (2010). Anosmia and hyposmia. Allergy and Asthma Proceedings, 31(3), 185. https://doi.org/10.2500/aap.2010.31.3357
Gug, I. et al. (2019). Salivary biomarkers detection: Analytical and immunological methods overview. TrAC Trends in Analytical Chemistry, 113, 301. https://doi.org/10.1016/j.trac.2019.02.020
Ingle, E. (2020). Artificial saliva for therapeutic management of xerostomia: A structured review. Journal of Oral Health and Community Dentistry, 14(1), 32. https://doi.org/10.5005/jp-journals-10062-0064
Khurshid, Z. et al. (2018). Role of salivary biomarkers in oral cancer detection. Advances in Clinical Chemistry, 23. https://doi.org/10.1016/bs.acc.2018.05.002 (Catatan: Volume 23, nomor halaman/artikel tidak ada)
Khurshid, Z. et al. (2016). Human saliva collection devices for proteomics: An update. International Journal of Molecular Sciences, 17(6), 846. https://doi.org/10.3390/ijms17060846
Krom, B. P. et al. (2014). Candida and other fungal species. Journal of Dental Research, 93(5), 445. https://doi.org/10.1177/0022034514521814
Lee, J. et al. (2009). Salivary diagnostics. Orthodontics and Craniofacial Research, 12(3), 206. https://doi.org/10.1111/j.1601-6343.2009.01454.x
Li, Y. et al. (2022). The oral microbiota and cardiometabolic health: A comprehensive review and emerging insights. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.1010368
Liu, J., & Duan, Y. (2012). Saliva: A potential media for disease diagnostics and monitoring. Oral Oncology, 48(7), 569. https://doi.org/10.1016/j.oraloncology.2012.01.021
Malon, R. S. P. et al. (2014). Saliva-based biosensors: Noninvasive monitoring tool for clinical diagnostics. BioMed Research International, 2014, 1. https://doi.org/10.1155/2014/962903
Mani, V. et al. (2020). Electrochemical sensors targeting salivary biomarkers: A comprehensive review. TrAC Trends in Analytical Chemistry, 135, 116164. https://doi.org/10.1016/j.trac.2020.116164
Marsh, P. D. (2006). Dental plaque as a biofilm and a microbial community – implications for health and disease. BMC Oral Health, 6(Suppl 1), S14. https://doi.org/10.1186/1472-6831-6-s1-s14
Mhatre, S. et al. (2024). Dry mouth dilemma: A comprehensive review of xerostomia in complete denture wearers. Cureus. https://doi.org/10.7759/cureus.58564
Milanowski, M. et al. (2016). Saliva – Volatile biomarkers and profiles. Critical Reviews in Analytical Chemistry, 47(3), 251. https://doi.org/10.1080/10408347.2016.1266925
Millsop, J. W. et al. (2017). Etiology, evaluation, and management of xerostomia. Clinics in Dermatology, 35(5), 468. https://doi.org/10.1016/j.clindermatol.2017.06.010
Miranda?Rius, J. et al. (2015). Salivary secretory disorders, inducing drugs, and clinical management. International Journal of Medical Sciences, 12(10), 811. https://doi.org/10.7150/ijms.12912
Mulhall, H. et al. (2020). Porphyromonas gingivalis, a long-range pathogen: Systemic impact and therapeutic implications. Microorganisms, 8(6), 869. https://doi.org/10.3390/microorganisms8060869
Napeñas, J. J. et al. (2009). Diagnosis and treatment of xerostomia (dry mouth). Odontology, 97(2), 76. https://doi.org/10.1007/s10266-008-0099-7
Newton, T. (2012). Interdisciplinary health promotion: A call for theory?based interventions drawing on the skills of multiple disciplines. Community Dentistry And Oral Epidemiology, 40, 49. https://doi.org/10.1111/j.1600-0528.2012.00720.x
Nobbs, A. H., & Kreth, J. (2019). Genetics of sanguinis-group streptococci in health and disease. Microbiology Spectrum, 7(1). https://doi.org/10.1128/microbiolspec.gpp3-0052-2018
Pedro, A. S. et al. (2008). Chitosan: An option for development of essential oil delivery systems for oral cavity care? Carbohydrate Polymers, 76(4), 501. https://doi.org/10.1016/j.carbpol.2008.12.016
Pittman, T. W. et al. (2023). Saliva-based microfluidic point-of-care diagnostic. Theranostics, 13(3), 1091. https://doi.org/10.7150/thno.78872
Rath, S. et al. (2021). Oral biofilm: Development mechanism, multidrug resistance, and their effective management with novel techniques. Rambam Maimonides Medical Journal, 12(1). https://doi.org/10.5041/rmmj.10428
Saleh, J. et al. (2014). Salivary hypofunction: An update on aetiology, diagnosis and therapeutics. Archives of Oral Biology, 60(2), 242. https://doi.org/10.1016/j.archoralbio.2014.10.004
Sánchez, C. et al. (2019). Use of electronic noses for diagnosis of digestive and respiratory diseases through the breath. Biosensors, 9(1), 35. https://doi.org/10.3390/bios9010035
Santos, V. C. E. dos et al. (2023). Effects of BlueM® against Streptococcus mutans biofilm and its virulence gene expression. Brazilian Dental Journal, 34(1), 19. https://doi.org/10.1590/0103-6440202305133
Schubert, J. K., & Geiger, K. (1999). Bedeutung und Perspektiven der Atemgasanalytik. AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie, 34(7), 391. https://doi.org/10.1055/s-1999-197
Spanemberg, J. C. et al. (2019). Quality of life related to oral health and its impact in adults. Journal of Stomatology Oral and Maxillofacial Surgery, 120(3), 234. https://doi.org/10.1016/j.jormas.2019.02.004
Spielman, A., & Forrai, J. (2023). History of halitosis. Kaleidoscope History, 13(26), 436. https://doi.org/10.17107/kh.2023.26.29
Stack, K. M., & Papas, A. (2001). Xerostomia: Etiology and clinical management. Nutrition in Clinical Care, 4(1), 15. https://doi.org/10.1046/j.1523-5408.2001.00103.x
Tong, F. et al. (2023). Characteristics of human and microbiome RNA profiles in saliva. RNA Biology, 20(1), 398. https://doi.org/10.1080/15476286.2023.2229596
Wijesinghe, G. K. et al. (2023). Cross-kingdom microbial interactions within the oral cavity and their implications for oral disease. Current Clinical Microbiology Reports, 10(2), 29. https://doi.org/10.1007/s40588-023-00191-9
Yakob, M. et al. (2014). Salivary biomarkers for detection of oral squamous cell carcinoma: Current state and recent advances. Current Oral Health Reports, 1(2), 133. https://doi.org/10.1007/s40496-014-0014-y
Zhang, A. et al. (2012). Salivary proteomics in biomedical research. Clinica Chimica Acta, 415, 261. https://doi.org/10.1016/j.cca.2012.11.001
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